“The economic consequences of COVID-19 will be particularly acute for those who are unstably housed, economically insecure, and who are dependent on social services,” Sandro Galea, MD, MPH, Dean, Boston University School of Public Health. “Individuals with SUD often face all three of these challenges, placing them at particularly high risk of experiencing poorer health due to COVID-19-induced societal shifts.” Our patients need strong leadership including reassurance from the health care system, from medical directors to social workers. Each staff member plays a critical role in caring for vulnerable patients.